I don't know what seems to be wrong i use lxqt with bspwm and picom with vsync enabled and blurred transparency with a transparent kvantum theme , i have a ryzen and a radeon pro when it freezes the hdd led blinks like the hard disk is working or something . Also i use apmd . I have an nvme disk and also performs very slow.
I remember i had no problems with mate or a mate desktop or openbox without picom vsync (with antitearing on amdgpu.conf)
Any ideas ??