Laptop=keybindings
Desktop=mouse+keybindings
I'll admit I enjoy the keyboard driven work flow on my laptop, it feels/is faster. But I agree with @rvp that sometimes a mouse is nice. Especially when web browsing. That reminds me to add something to the Wishlist for NetBSD 10 thread--better support for Synaptics track pads so we can get 2 finger scrolling working!
More to the point, I'm a fan of Plan9 which is a predominantly mouse driven OS, but I'd never install it on a laptop